Decreased Neurotrophin TrkB Receptor Expression Reduces Lesion Size in the Apolipoprotein E–Null Mutant Mouse
Circulation Kraemer et al.
112: 3644
Data Supplement
Files in this Data Supplement:
- Supplemental Methods
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(Microsoft Word) (47 KB)
- Table I
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(Microsoft Word) (31 KB)
- Table II
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(Microsoft Word) (28 KB)
- Figure I
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(Microsoft Office Imaging file) (8.41 MB). Immunoprecipitation/Western blot analysis for expression of Trk B in the aorta of Apo E (-/-) mice. Lane 1. Brain lysate from Trk B (+/+)|Apo E (-/-) mouse. Lane 2. Lysate from aorta from Trk B (+/+)|Apo E (-/-) mouse. Lane 3. Lysate from aorta from Trk B (+/-)|Apo E (-/-) mouse. This represents one of 3 replicate experiments.
- Figure II
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(Microsoft Office Imaging file)(3.28 MB). PCR of genomic DNA isolated from the tail (Panel A) or peritoneal macrophages (Panel B) of irradiated Trk B (+/+) mice transplanted with bone marrow from Trk B (+/-) mice. Tail DNA was obtained prior to transplantation. Lane 1. (+) allele positive control. Lane 2. (-) allele positive control. Lanes 3-5. DNA from 3 different Trk B (+/+) mice.
