Step
|
Calcium Channel Blocker Regimen
|
ß-Blocker–Based Regimen
|
| 1 |
Amlodipine 5 mg |
Atenolol 50 mg |
| 2 |
Amlodipine 10 mg |
Atenolol 100 mg |
| 3 |
Amlodipine 10 mg+perindopril 4 mg |
Atenolol 100 mg+bendroflumethiazide K 1.25 mg |
| 4 |
Amlodipine 10 mg+perindopril 8 mg (2x mg) |
Atenolol 100 mg+bendroflumethiazide K 2.5 mg |
| 5 |
Amlodipine 10 mg+perindopril 8 mg (2x4 mg)+ doxazosin gastrointestinal transport system 4 mg |
Atenolol 100 mg+bendroflumethiazide K 2.5 mg+ doxazosin gastrointestinal transportsystem 4 mg |
| 6 |
Amlodipine 10 mg+perindopril 8 mg (2x4 mg)+ doxazosin gastrointestinal transport system 8 mg |
Atenolol 100 mg+bendroflumethiazide K 2.5 mg+ doxazosin gastrointestinal transport system 8 mg |
|
| Further treatment to achieve blood pressure goal is outlined at http://www.ascotstudy.org. All drugs were given orally. |
