X-Ray Fused With Magnetic Resonance Imaging (XFM) to Target Endomyocardial Injections: Validation in a Swine Model of Myocardial Infarction
Circulation de Silva et al.
114: 2342
Data Supplement
Files in this Data Supplement:
- Movie I
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(AVI) (229 KB) Two separate radiocontrast ventriculograms are shown under XFM, in the left anterior oblique (LAO, left) and right anterior oblique (RAO, right) projections. ECG-gated regions of interest from MRI are fused with the matching phase of the real-time cardiac cycle under x-ray. The endocardial contour is colored red, and the epicardial left ventricular contour is colored blue. Multimodality external fiducial markers are affixed to the skin. This animal underwent myocardial infarction in the LAD territory three days previously. There is good concordance between imaging modalities.
- Movie II
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(AVI) (1.21 MB) Two separate cineangiography loops under XFM immediately prior to injection of labeled MSCs. The left panel shows a LAO projection, and the right panel a RAO projection. ECG-gated regions of interest from MRI are fused with the matching phase of the real-time cardiac cycle under x-ray. The endocardial contour is colored red, and the epicardial left ventricular contour is colored blue. A static contour from an end-diastolic delayed hyperenhancement MRI is colored yellow. Multimodality external fiducial markers are affixed to the skin. Two prior injections are marked as yellow dots and numbered. The planned (3rd) injection, intended for the anteroseptal infarct border, appears overlapped in the LAO projection but distinct in the RAO projection.