Suppression of Atherosclerotic Plaque Progression and Instability by Tissue Inhibitor of Metalloproteinase-2: Involvement of Macrophage Migration and Apoptosis
Circulation Johnson et al.
113: 2435
Data Supplement
Files in this Data Supplement:
- Supplemental Methods
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(Word) (51 KB)
- Figure I
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(Power Point) (656 KB) Optimization of in vivo gene transfer in apoE-/- mice. Representative macroscopic cross sections of X-gal-stained murine liver to reveal adenovirus infection. The scale bar in Panel A represents 1 mm and is applicable to both panels. A: Pre-dosed with empty adenovirus (RAd66). B: Without pre-dosing.
- Figure II
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(Power Point) (1.89 MB) Effect of HD-AdTIMP-2 infection on atherosclerotic lesion collagen content. Representative sections of Picrosirius red stained brachiocephalic atherosclerotic lesions viewed under polarised light. Scale bar in panel (A) represents 500 μm and is applicable to all panels. A: Uninfected. B: Mice infected with HD-AdEmpty. C: Mice infected with HD-AdTIMP-2.
