Files in this Data Supplement:

• Table - (Word) (75.0 KB)
• Figure I - (Power Point) (133 KB) Cardiosphere phenotype. Cardiospheres were paraffin-embedded and sectioned prior to immunostaining to verify the results obtained in whole mount staining. Fluorescence confocal analysis of human cardiospheres in section for: c-Kit, CD105, and connexin 43. All show a staining pattern similar to that seen in Fig. 2 for cardiospheres in whole mount.
• Figure II - (Power Point) (79.5 KB) Fibroblast phenotype. Flow cytometric analysis performed using human skin fibroblasts. Isotype control histograms are depicted with a red fill.
• Figure IIIA - (TIF) (8.26 MB) Calculating regeneration. Masson's Trichrome staining is shown for a representative CDC-injected mouse. The total infarct zone is outlined in yellow in IIIB and IIIC.
• Figure IIIB - (TIF) (2.18 MB) Calculating regeneration. Areas of fibrosis are shown in red after image processing.
• Figure IIIC - (TIF) (2.18 MB) Calculating regeneration. Areas of viable myocardium are shown in red after image processing. Six sections were analyzed per animal and an average taken.
• Movie I - (AVI) (7.91 MB) Baseline echocardiogram. Example echocardiogram is shown for a mouse at baseline, prior to surgery.
• Movie II - (AVI) (9.02 MB) Echocardiogram 2 days post-infarction. Example echocardiogram is shown for a mouse 2 days after surgery and myocardial infarction.
• Movie III - (AVI) (4.72 MB) CDC-injected mouse echocardiogram. Example echocardiogram is shown for a CDC-injected mouse at 20 days. Note the motion in the anterior wall 20 days after infarction.
• Movie IV - (AVI) (7.88 MB) Fibroblast-injected mouse echocardiogram. Example echocardiogram is shown for a fibroblast-injected mouse at 20 days.