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(Circulation. 1950;1:246.)
© 1950 American Heart Association, Inc.

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Subendocardial Infarction: Report of Six Cases and Critical Survey of the Literature

HAROLD D. LEVINE M.D.¹ RALPH V. FORD M.D.¹

¹ From the Medical Clinic and Department of Pathology, Peter Bent Brigham Hospital, and the Departments of Medicine and Pathology, Harvard Medical School, Boston, Mass.

In the ordinary evolution of an acute myocardial infarct the electrocardiogram shows T wave (ischemia), RS-T segment ("current of injury") and QRS (death of muscle) changes. This paper presents a special group of cases of infarction in which only T wave and RS-T segment changes developed even when patients were observed over a considerable period. Therefore, the curves as such could not be considered diagnostic of myocardial infarction. The authors here describe a unique and intriguing group of cases of fatal myocardial infarction with electrocardiograms resembling those seen in stress tests for coronary insufficiency and showing rimlike subendocardial infarcts at postmortem.