This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by SHAFFER, A. B. Articles by KATZ, L. N. Search for Related Content PubMed PubMed Citation Articles by SHAFFER, A. B. Articles by KATZ, L. N.

(Circulation. 1954;10:527.)
© 1954 American Heart Association, Inc.

---

Observations on the Interatrial Pressure Gradients in Man

A. B. SHAFFER M.D.¹; E. N. SILBER M.D.¹; L. N. KATZ M.D.¹

¹ From the Cardiovascular Department, Medical Research Institute, Michael Reese Hospital, Chicago, Ill.

It was possible to calculate pressure gradients across the interatrial septum in several cases of congenital heart disease. Gradients in cases of interatrial septal defect are similar to those found in animals with artificially produced defects. The data are used to form a rounded picture of the hemodynamics of interatrial septal defect. In pulmonic stenosis with interatrial communication, reversal of the usual left-to-right gradient may occur only during atrial systole. Under these circumstances it is often possible to distinguish a patent foramen ovale with competent valve from an interatrial septal defect.

This article has been cited by other articles:

				L. A. SOLOFF and J. ZATUCHNI EMBOLIC OCCLUSION OF PATENT FORAMEN OVALE Arch Intern Med, September 1, 1956; 98(3): 344 - 347. [Abstract] [PDF]