Circulation. 2004;110:66-73
Published online before print June 14, 2004, doi: 10.1161/01.CIR.0000133276.45198.A5
Published online before print June 14, 2004, doi: 10.1161/01.CIR.0000133276.45198.A5
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
(Circulation. 2004;110:66-73.)
© 2004 American Heart Association, Inc.
Original Articles |
Tissue Doppler Imaging Is Superior to Strain Rate Imaging and Postsystolic Shortening on the Prediction of Reverse Remodeling in Both Ischemic and Nonischemic Heart Failure After Cardiac Resynchronization Therapy
From the Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong (C.-M.Y., J.W.-H.F., Q.Z., Y.-S.C., H.L., L.C.C.K., S.-L.K., Y.Z., J.E.S.), and the Department of Medicine, Alice Ho Miu Ling Nethersole Hospital (C.-K.C.), Hong Kong.
Correspondence to Professor Cheuk-Man Yu, Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong. E-mail cmyu{at}cuhk.edu.hk
Received June 17, 2003; de novo received September 13, 2003; revision received March 10, 2004; accepted March 17, 2004.
Background— A number of noninvasive techniques have been used to predict the effectiveness of cardiac resynchronization therapy (CRT) in heart failure patients, in particular left ventricular (LV) reverse remodeling. This study compared the relative predictive values of tissue Doppler imaging (TDI) and strain-rate imaging (SRI) parameters for LV reverse remodeling in patients who received CRT and examined for potential differences in ischemic (n=22) and nonischemic (n=32) heart failure.
Methods and Results— TDI and SRI were performed at baseline and 3-month follow-up. Eighteen parameters of intraventricular and interventricular asynchrony based on the time to peak myocardial contraction (Ts) and time to peak strain rate (Tsr) were compared, along with postsystolic shortening (PSS). Reverse remodeling with reduction of LV end-diastolic and end-systolic volumes and gain in ejection fraction (all P<0.001) was observed in the whole study population. The standard deviation of Ts of 12 LV segments (Ts-SD) is the most powerful predictor of reverse remodeling in both the ischemic (r=–0.65, P<0.001) and nonischemic (r=–0.79, P<0.001) groups. The PSS of 12 LV segments was a good predictor only for the nonischemic (r=–0.64, P<0.001) but not the ischemic (r=0.32, P=NS) group. However, parameters of SRI and interventricular asynchrony failed to predict reverse remodeling. By multiple regression analysis, independent parameters included Ts-SD in both groups (P<0.005) and PSS of 12 LV segments in the nonischemic group (P=0.03). The area of the receiver operating characteristic curve was largest for Ts-SD (0.94; CI=0.88 to 1.00).
Conclusions— Ts-SD is the most powerful predictor of LV reverse remodeling and was consistently useful for ischemic and nonischemic heart failure. However, PSS is useful only for nonischemic pathogenesis, whereas the role of SRI parameters was not supported by the present study.
Key Words: heart failure • remodeling • pacing • echocardiography
This article has been cited by other articles:
 |
|
 |
|
  P. Lim, A. Buakhamsri, Z. B. Popovic, N. L. Greenberg, D. Patel, J. D. Thomas, and R. A. Grimm Longitudinal Strain Delay Index by Speckle Tracking Imaging: A New Marker of Response to Cardiac Resynchronization Therapy Circulation, September 9, 2008; 118(11): 1130 - 1137. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S-A Chang, H-K Kim, H-Y Lee, S-Y Choi, B-K Koo, Y-J Kim, D-W Sohn, B-H Oh, Y-B Park, Y-S Choi, et al. Restoration of left ventricular synchronous contraction after acute myocardial infarction by stem cell therapy: new insights into the therapeutic implication of stem cell therapy for acute myocardial infarction Heart, August 1, 2008; 94(8): 995 - 1001. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M Marciniak, B Bijnens, A Baltabaeva, A Marciniak, C Parsai, P Claus, and G R Sutherland Interventricular interaction as a possible mechanism for the presence of a biphasic systolic velocity profile in normal left ventricular free walls Heart, August 1, 2008; 94(8): 1058 - 1064. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. H. Lim, G. Y.H. Lip, and J. E. Sanderson Ventricular optimization of biventricular pacing: a systematic review Europace, July 8, 2008; (2008) eun177v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Miyazaki, G. Lin, B. D. Powell, R. E. Espinosa, C. J. Bruce, F. A. Miller Jr, B. L. Karon, R. F. Rea, D. L. Hayes, and J. K. Oh Strain Dyssynchrony Index Correlates With Improvement in Left Ventricular Volume After Cardiac Resynchronization Therapy Better Than Tissue Velocity Dyssynchrony Indexes Circ Cardiovasc Imaging, July 1, 2008; 1(1): 14 - 22. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. K. Friedberg, S. L. Roche, A. F. Mohammed, M. Balasingam, E. G. Atenafu, and P. F. Kantor Left Ventricular Diastolic Mechanical Dyssynchrony and Associated Clinical Outcomes in Children With Dilated Cardiomyopathy Circ Cardiovasc Imaging, July 1, 2008; 1(1): 50 - 57. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Abraham and T. P. Abraham Is echocardiographic assessment of dyssynchrony useful to select candidates for cardiac resynchronization therapy?: Echocardiography Is Useful Before Cardiac Resynchronization Therapy if QRS Duration Is Available Circ Cardiovasc Imaging, July 1, 2008; 1(1): 79 - 85. [Full Text] [PDF]
|
|
|
|
 |
|
 A. H.M. Jansen, F. Bracke, J. m. van Dantzig, K. H. Peels, J. C. Post, H. C.M. van den Bosch, B. van Gelder, A. Meijer, H. H.M. Korsten, J. de Vries, et al. The influence of myocardial scar and dyssynchrony on reverse remodeling in cardiac resynchronization therapy Eur J Echocardiogr, July 1, 2008; 9(4): 483 - 488. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. S. Chung, A. R. Leon, L. Tavazzi, J.-P. Sun, P. Nihoyannopoulos, J. Merlino, W. T. Abraham, S. Ghio, C. Leclercq, J. J. Bax, et al. Results of the Predictors of Response to CRT (PROSPECT) Trial Circulation, May 20, 2008; 117(20): 2608 - 2616. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Miyazaki, B. D. Powell, C. J. Bruce, R. E. Espinosa, M. M. Redfield, F. A. Miller, D. L. Hayes, Y.-M. Cha, and J. K. Oh Comparison of Echocardiographic Dyssynchrony Assessment by Tissue Velocity and Strain Imaging in Subjects With or Without Systolic Dysfunction and With or Without Left Bundle-Branch Block Circulation, May 20, 2008; 117(20): 2617 - 2625. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. J. Anderson, C. Miyazaki, G. R. Sutherland, and J. K. Oh Patient Selection and Echocardiographic Assessment of Dyssynchrony in Cardiac Resynchronization Therapy Circulation, April 15, 2008; 117(15): 2009 - 2023. [Full Text] [PDF]
|
|
|
|
|
|
J. van Dijk, P. Knaapen, I.K. Russel, T. Hendriks, C.P. Allaart, C.C. de Cock, and O. Kamp Mechanical dyssynchrony by 3D echo correlates with acute haemodynamic response to biventricular pacing in heart failure patients Europace, January 1, 2008; 10(1): 63 - 68. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. van Dijk, P. A. Dijkmans, M. J.W. Gotte, M. D. Spreeuwenberg, C. A. Visser, and O. Kamp Evaluation of global left ventricular function and mechanical dyssynchrony in patients with an asymptomatic left bundle branch block: a real-time 3D echocardiography study Eur J Echocardiogr, January 1, 2008; 9(1): 40 - 46. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Leclercq, G. B. Bleeker, C. Linde, E. Donal, J. J. Bax, M. J. Schalij, and C. Daubert Cardiac resynchronization therapy: clinical results and evolution of candidate selection Eur. Heart J. Suppl., December 1, 2007; 9(suppl_I): I94 - I106. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. P. Abraham, V. L. Dimaano, and H.-Y. Liang Role of Tissue Doppler and Strain Echocardiography in Current Clinical Practice Circulation, November 27, 2007; 116(22): 2597 - 2609. [Full Text] [PDF]
|
|
|
|
 |
|
 A. D'Andrea, P. Caso, S. Romano, R. Scarafile, L. Riegler, G. Salerno, G. Limongelli, G. Di Salvo, P. Calabro, L. Del Viscovo, et al. Different effects of cardiac resynchronization therapy on left atrial function in patients with either idiopathic or ischaemic dilated cardiomyopathy: a two-dimensional speckle strain study Eur. Heart J., November 2, 2007; 28(22): 2738 - 2748. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Yoshida, Y. Seo, H. Yamasaki, K. Tanoue, N. Murakoshi, T. Ishizu, Y. Sekiguchi, S. Kawano, S. Otsuka, S. Watanabe, et al. Effect of triangle ventricular pacing on haemodynamics and dyssynchrony in patients with advanced heart failure: a comparison study with conventional bi-ventricular pacing therapy Eur. Heart J., November 1, 2007; 28(21): 2610 - 2619. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. B Bleeker, C.-M. Yu, P. Nihoyannopoulos, J. de Sutter, N. Van de Veire, E. R Holman, M. J Schalij, E. E van der Wall, and J. J Bax Optimal use of echocardiography in cardiac resynchronisation therapy Heart, November 1, 2007; 93(11): 1339 - 1350. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Johnson, H. K. Kim, M. Tanabe, J. Gorcsan, D. Schwartzman, S. G. Shroff, and M. R. Pinsky Differential effects of left ventricular pacing sites in an acute canine model of contraction dyssynchrony Am J Physiol Heart Circ Physiol, November 1, 2007; 293(5): H3046 - H3055. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Gorcsan III, M. Tanabe, G. B. Bleeker, M. S. Suffoletto, N. C. Thomas, S. Saba, L. F. Tops, M. J. Schalij, and J. J. Bax Combined Longitudinal and Radial Dyssynchrony Predicts Ventricular Response After Resynchronization Therapy J. Am. Coll. Cardiol., October 9, 2007; 50(15): 1476 - 1483. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Vitarelli, P. Franciosa, and S. Rosanio Tissue Doppler Imaging in the assessment of selection and response from cardiac resynchronization therapy Eur J Echocardiogr, October 1, 2007; 8(5): 309 - 316. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Sirker, M. Thomas, S. Baker, J. Shrimpton, S. Jewell, L. Lee, R. Rankin, V. Griffiths, N. Cooter, R. James, et al. Cardiac resynchronization therapy: left or left-and-right for optimal symptomatic effect the LOLA ROSE study Europace, October 1, 2007; 9(10): 862 - 868. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Authors/Task Force Members, P. E. Vardas, A. Auricchio, J.-J. Blanc, J.-C. Daubert, H. Drexler, H. Ector, M. Gasparini, C. Linde, F. B. Morgado, et al. Guidelines for cardiac pacing and cardiac resynchronization therapy: The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in Collaboration with the European Heart Rhythm Association Europace, October 1, 2007; 9(10): 959 - 998. [Full Text] [PDF]
|
|
|
|
|
|
M. I Burgess, C. Jenkins, J. Chan, and T. H Marwick Measurement of left ventricular dyssynchrony in patients with ischaemic cardiomyopathy: a comparison of real-time three-dimensional and tissue Doppler echocardiography Heart, October 1, 2007; 93(10): 1191 - 1196. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. A. Kass Highlighting the R in CRT Circulation, September 25, 2007; 116(13): 1434 - 1436. [Full Text] [PDF]
|
|
|
|
|
|
G. B. Bleeker, S. A. Mollema, E. R. Holman, N. Van De Veire, C. Ypenburg, E. Boersma, E. E. van der Wall, M. J. Schalij, and J. J. Bax Left Ventricular Resynchronization Is Mandatory for Response to Cardiac Resynchronization Therapy: Analysis in Patients With Echocardiographic Evidence of Left Ventricular Dyssynchrony at Baseline Circulation, September 25, 2007; 116(13): 1440 - 1448. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Authors/Task Force Members, P. E. Vardas, A. Auricchio, J.-J. Blanc, J.-C. Daubert, H. Drexler, H. Ector, M. Gasparini, C. Linde, F. B. Morgado, et al. Guidelines for cardiac pacing and cardiac resynchronization therapy: The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in Collaboration with the European Heart Rhythm Association Eur. Heart J., September 2, 2007; 28(18): 2256 - 2295. [Full Text] [PDF]
|
|
|
|
|
|
J. Madaric, M. Vanderheyden, C. Van Laethem, K. Verhamme, A. Feys, M. Goethals, S. Verstreken, P. Geelen, M. Penicka, B. De Bruyne, et al. Early and late effects of cardiac resynchronization therapy on exercise-induced mitral regurgitation: relationship with left ventricular dyssynchrony, remodelling and cardiopulmonary performance Eur. Heart J., September 1, 2007; 28(17): 2134 - 2141. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Lim, C. Bars, L. Mitchell-Heggs, C. Roiron, N. Elbaz, B. Hamdaoui, N. Lellouche, J.-L. Dubois-Rande, and P. Gueret Importance of contractile reserve for CRT Europace, September 1, 2007; 9(9): 739 - 743. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Lenarczyk, O. Kowalski, T. Kukulski, M. Szulik, P. Pruszkowska-Skrzep, T. Zielinska, J. Kowalczyk, S. Pluta, A. Duszanska, B. Sredniawa, et al. Triple-site biventricular pacing in patients undergoing cardiac resynchronization therapy: a feasibility study Europace, September 1, 2007; 9(9): 762 - 767. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-M. Yu, F. Fang, Q. Zhang, G. W.K. Yip, C. M. Li, J. Y.-S. Chan, L. Wu, and J. W.-H. Fung Improvement of Atrial Function and Atrial Reverse Remodeling After Cardiac Resynchronization Therapy for Heart Failure J. Am. Coll. Cardiol., August 21, 2007; 50(8): 778 - 785. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. K.Y. Chan, J. E. Sanderson, T. Wang, W. Lam, G. Yip, M. Wang, Y.-Y. Lam, Y. Zhang, L. Yeung, E. B. Wu, et al. Aldosterone Receptor Antagonism Induces Reverse Remodeling When Added to Angiotensin Receptor Blockade in Chronic Heart Failure J. Am. Coll. Cardiol., August 14, 2007; 50(7): 591 - 596. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
U. Wisloff, A. Stoylen, J. P. Loennechen, M. Bruvold, O. Rognmo, P. M. Haram, A. E. Tjonna, J. Helgerud, S. A. Slordahl, S. J. Lee, et al. Superior Cardiovascular Effect of Aerobic Interval Training Versus Moderate Continuous Training in Heart Failure Patients: A Randomized Study Circulation, June 19, 2007; 115(24): 3086 - 3094. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-M. Yu, J. E. Sanderson, T. H. Marwick, and J. K. Oh Tissue Doppler Imaging: A New Prognosticator for Cardiovascular Diseases J. Am. Coll. Cardiol., May 15, 2007; 49(19): 1903 - 1914. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. D'Andrea, P. Caso, S. Cuomo, R. Scarafile, G. Salerno, G. Limongelli, G. Di Salvo, S. Severino, L. Ascione, P. Calabro, et al. Effect of dynamic myocardial dyssynchrony on mitral regurgitation during supine bicycle exercise stress echocardiography in patients with idiopathic dilated cardiomyopathy and 'narrow' QRS Eur. Heart J., April 2, 2007; 28(8): 1004 - 1011. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. W H Fung, J. Y S Chan, G. W K Yip, H. C K Chan, W. W L Chan, Q. Zhang, and C.-M. Yu Effect of left ventricular endocardial activation pattern on echocardiographic and clinical response to cardiac resynchronization therapy Heart, April 1, 2007; 93(4): 432 - 437. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.K. Oh Echocardiography in heart failure: Beyond diagnosis Eur J Echocardiogr, January 1, 2007; 8(1): 4 - 14. [Full Text] [PDF]
|
|
|
|
|
|
J. A. White, R. Yee, X. Yuan, A. Krahn, A. Skanes, M. Parker, G. Klein, and M. Drangova Delayed Enhancement Magnetic Resonance Imaging Predicts Response to Cardiac Resynchronization Therapy in Patients With Intraventricular Dyssynchrony J. Am. Coll. Cardiol., November 21, 2006; 48(10): 1953 - 1960. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-M. Yu, Q. Zhang, G. W.K. Yip, P.-W. Lee, L. C.C. Kum, Y.-Y. Lam, and J. W.-H. Fung Diastolic and Systolic Asynchrony in Patients With Diastolic Heart Failure: A Common but Ignored Condition J. Am. Coll. Cardiol., October 31, 2006; (2006) j.jacc.2006.10.022v1. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. E. Sanderson Systolic and Diastolic Ventricular Dyssynchrony in Systolic and Diastolic Heart Failure J. Am. Coll. Cardiol., October 31, 2006; (2006) j.jacc.2006.10.024v1. [Full Text] [PDF]
|
|
|
|
|
|
J. E. Sanderson Assessment of ventricular dyssynchrony: global or regional function? Eur. Heart J., October 2, 2006; 27(20): 2380 - 2381. [Full Text] [PDF]
|
|
|
|
|
|
E. C. Stecker, M. Zargarian, V. Dogra, B. T. John, J. Kron, J. H. McAnulty, and S. S. Chugh Native QRS duration predicts the occurrence of arrhythmic events in ICD recipients Europace, October 1, 2006; 8(10): 859 - 862. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C-M Yu, Q Zhang, Y-S Chan, C-K Chan, G W K Yip, L C C Kum, E B Wu, P-W Lee, Y-Y Lam, S Chan, et al. Tissue Doppler velocity is superior to displacement and strain mapping in predicting left ventricular reverse remodelling response after cardiac resynchronisation therapy Heart, October 1, 2006; 92(10): 1452 - 1456. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Lafitte, P. Bordachar, M. Lafitte, S. Garrigue, S. Reuter, P. Reant, K. Serri, V. Lebouffos, M. Berrhouet, P. Jais, et al. Dynamic Ventricular Dyssynchrony: An Exercise-Echocardiography Study J. Am. Coll. Cardiol., June 6, 2006; 47(11): 2253 - 2259. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Q. Zhang, J. W.-H. Fung, A. Auricchio, J. Y.-S. Chan, L. C.C. Kum, L. W. Wu, and C.-M. Yu Differential change in left ventricular mass and regional wall thickness after cardiac resynchronization therapy for heart failure Eur. Heart J., June 2, 2006; 27(12): 1423 - 1430. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. M. Hawkins, M. C. Petrie, M. R. MacDonald, K. J. Hogg, and J. J.V. McMurray Selecting patients for cardiac resynchronization therapy: electrical or mechanical dyssynchrony? Eur. Heart J., June 1, 2006; 27(11): 1270 - 1281. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Mele, G. Pasanisi, F. Capasso, A. De Simone, M.-A. Morales, D. Poggio, A. Capucci, G. Tabacchi, L. Sallusti, and R. Ferrari Left intraventricular myocardial deformation dyssynchrony identifies responders to cardiac resynchronization therapy in patients with heart failure Eur. Heart J., May 1, 2006; 27(9): 1070 - 1078. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. H. Marwick Measurement of Strain and Strain Rate by Echocardiography: Ready for Prime Time? J. Am. Coll. Cardiol., April 4, 2006; 47(7): 1313 - 1327. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G B Bleeker, P Steendijk, E R Holman, C-M Yu, O A Breithardt, T A M Kaandorp, M J Schalij, E E van der Wall, P Nihoyannopoulos, and J J Bax Assessing right ventricular function: the role of echocardiography and complementary technologies Heart, April 1, 2006; 92(suppl_1): i19 - i26. [Full Text] [PDF]
|
|
|
|
|
|
C. Y. Ho and S. D. Solomon A Clinician's Guide to Tissue Doppler Imaging Circulation, March 14, 2006; 113(10): e396 - e398. [Full Text] [PDF]
|
|
|
|
|
|
F. A Flachskampf and J.-U. Voigt Echocardiographic methods to select candidates for cardiac resynchronisation therapy. Heart, March 1, 2006; 92(3): 424 - 429. [Full Text] [PDF]
|
|
|
|
|
|
G. B. Bleeker, T. A.M. Kaandorp, H. J. Lamb, E. Boersma, P. Steendijk, A. de Roos, E. E. van der Wall, M. J. Schalij, and J. J. Bax Effect of Posterolateral Scar Tissue on Clinical and Echocardiographic Improvement After Cardiac Resynchronization Therapy Circulation, February 21, 2006; 113(7): 969 - 976. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. S. Suffoletto, K. Dohi, M. Cannesson, S. Saba, and J. Gorcsan III Novel Speckle-Tracking Radial Strain From Routine Black-and-White Echocardiographic Images to Quantify Dyssynchrony and Predict Response to Cardiac Resynchronization Therapy Circulation, February 21, 2006; 113(7): 960 - 968. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S Ellery, L Williams, and M Frenneaux Role of resynchronisation therapy and implantable cardioverter defibrillators in heart failure Postgrad. Med. J., |