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(Circulation. 1958;18:1125.)
© 1958 American Heart Association, Inc.

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Studies of the Arterial Pulse Wave

ARTHUR W. FEINBERG M.D.¹; HENRY LAX M.D.¹; William Urban ¹

¹ From the Research Service, First (Columbia University) Division, Goldwater Memorial Hospital, Department of Hospitals, New York, N.Y., and the Department of Medicine, College of Physicians and Surgeons, Columbia University.

Previous studies have shown abnormalities of the arterial pulse wave in hypertensive subjects of all age groups. The major change has been diminution to disappearance of the dicrotic wave. The pharmacologic differences between epinephrine and norepinephrine offer a means of studying the mechanism of this change in the dicrotic wave. In the present study, normotensive subjects have had transient hypertension induced by the infusion of epinephrine and norepinephrine. The different effects of these drugs on their arterial pulse waves have been recorded.

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