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(Circulation. 1950;2:530.)
© 1950 American Heart Association, Inc.

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Efficiency of Heparin in Retarding Media on the Maintenance of a Decreased Coagulability of the Blood

HELEN I. GLUECK M.D.¹; CLARENCE J. PODORE M.D.¹; JOSEPH E. LEVINSON M.D.¹

¹ From The May Institute for Medical Research and the Department of Internal Medicine, The Jewish Hospital, Cincinnati, Ohio.

Heparin/Pitkin menstruum has been advocated in the therapy of a variety of thromboembolic disorders. The clinical properties of two such mixtures each with and without vasoconstrictor agents is evaluated and it is demonstrated that a significant prolongation of the clotting time beyond 24 hours cannot be obtained. A comparison between the one tube and the three tube methods for the determination of the coagulation time of blood reveals that both procedures yield comparable data.