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(Circulation. 1967;36:187.)
© 1967 American Heart Association, Inc.

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Myocardial Blood Flow in Man as Measured by a Coincidence Counting System and a Single Bolus of ⁸⁴RbCl

SUZANNE B. KNOEBEL M.D.¹; PAUL L. MCHENRY M.D.¹; LEON STEIN M.D.¹; AHMET SONEL M.D.¹

¹ From the Department of Medicine, Indiana University School of Medicine, and the Krannert Institute of Cardiology, Marion County General Hospital, Indianapolis, Indiana.

Utilizing a coincidence counting system for the measurement of myocardial uptake of an 84-rubidium indicator, resting coronary blood flow (CBF) was measured in 33 normal subjects. The average CBF was 269 ± 61 ml/min/total heart. This represented 5.2 ± 1.6% of the simultaneous cardiac output. Fourteen normal subjects had resting and exercising CBF measurements. The change in CBF with exercise was statistically significant (0.005 > P > 0.001). The characteristics of the method are discussed in relationship to possible clinical applications for the measurement of CBF.

Key Words: Coronary blood flow • Coronary sclerosis • Cardiac output • Exercise

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