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Volume 115, Issue 4; January 30, 2007
Issue Highlights
Editorials
Original Articles
Arrhythmia/Electrophysiology
Epidemiology
Exercise Physiology
Heart Failure
Molecular Cardiology
Vascular Medicine
Basic Science for Clinicians
Congenital Heart Disease for the Adult Cardiologist
Images in Cardiovascular Medicine
Correspondence
European Perspectives
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Issue Highlights:
Issue Highlights
Circulation. 2007;115:427
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Editorials:
A Failure to Adapt: Ankyrins in Congenital and Acquired Arrhythmias
Gordon F. Tomaselli
Circulation. 2007;115:428-429, doi:10.1161/CIRCULATIONAHA.106.675389
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Should Early Acceleration of Heart Rate During Exercise Be Used to Risk Stratify Patients With Suspected or Established Coronary Artery Disease?
Bernard R. Chaitman
Circulation. 2007;115:430-431, doi:10.1161/CIRCULATIONAHA.106.676882
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Original Articles:
Arrhythmia/Electrophysiology:
Defining the Cellular Phenotype of "Ankyrin-B Syndrome" Variants: Human
ANK2
Variants Associated With Clinical Phenotypes Display a Spectrum of Activities in Cardiomyocytes
Peter J. Mohler, Solena Le Scouarnec, Isabelle Denjoy, John S. Lowe, Pascale Guicheney, Lise Caron, Iwona M. Driskell, Jean-Jacques Schott, Kris Norris, Antoine Leenhardt, Richard B. Kim, Denis Escande, and Dan M. Roden
Circulation. 2007;115:432-441; published online before print January 22 2007, doi:10.1161/CIRCULATIONAHA.106.656512
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Clinical Perspective
Loss-of-Function Mutations in the Cardiac Calcium Channel Underlie a New Clinical Entity Characterized by ST-Segment Elevation, Short QT Intervals, and Sudden Cardiac Death
Charles Antzelevitch, Guido D. Pollevick, Jonathan M. Cordeiro, Oscar Casis, Michael C. Sanguinetti, Yoshiyasu Aizawa, Alejandra Guerchicoff, Ryan Pfeiffer, Antonio Oliva, Bernd Wollnik, Philip Gelber, Elias P. Bonaros, Jr, Elena Burashnikov, Yuesheng Wu, John D. Sargent, Stefan Schickel, Ralf Oberheiden, Atul Bhatia, Li-Fern Hsu, Michel Haïssaguerre, Rainer Schimpf, Martin Borggrefe, and Christian Wolpert
Circulation. 2007;115:442-449; published online before print January 15 2007, doi:10.1161/CIRCULATIONAHA.106.668392
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Clinical Perspective
Epidemiology:
Triglycerides and the Risk of Coronary Heart Disease: 10 158 Incident Cases Among 262 525 Participants in 29 Western Prospective Studies
Nadeem Sarwar, John Danesh, Gudny Eiriksdottir, Gunnar Sigurdsson, Nick Wareham, Sheila Bingham, S. Matthijs Boekholdt, Kay-Tee Khaw, and Vilmundur Gudnason
Circulation. 2007;115:450-458; published online before print December 26 2006, doi:10.1161/CIRCULATIONAHA.106.637793
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CME
Prediction of Clinical Cardiovascular Events With Carotid Intima-Media Thickness: A Systematic Review and Meta-Analysis
Matthias W. Lorenz, Hugh S. Markus, Michiel L. Bots, Maria Rosvall, and Matthias Sitzer
Circulation. 2007;115:459-467; published online before print January 22 2007, doi:10.1161/CIRCULATIONAHA.106.628875
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Exercise Physiology:
Prognostic Value of Heart Rate Increase at Onset of Exercise Testing
Nicholas J. Leeper, Frederick E. Dewey, Euan A. Ashley, Marcus Sandri, Swee Yaw Tan, David Hadley, Jonathan Myers, and Victor Froelicher
Circulation. 2007;115:468-474; published online before print January 22 2007, doi:10.1161/CIRCULATIONAHA.106.666388
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Clinical Perspective
Heart Failure:
Increased Expression of Syndecan-1 Protects Against Cardiac Dilatation and Dysfunction After Myocardial Infarction
Davy Vanhoutte, Mark W.M. Schellings, Martin Götte, Melissa Swinnen, Veronica Herias, Martin K. Wild, Dietmar Vestweber, Emmanuel Chorianopoulos, Víctor Cortés, Attilio Rigotti, Mary-Ann Stepp, Frans Van de Werf, Peter Carmeliet, Yigal M. Pinto, and Stephane Heymans
Circulation. 2007;115:475-482; published online before print January 22 2007, doi:10.1161/CIRCULATIONAHA.106.644609
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Molecular Cardiology:
Neuronal Nitric Oxide Synthase Signaling in the Heart Is Regulated by the Sarcolemmal Calcium Pump 4b
Delvac Oceandy, Elizabeth J. Cartwright, Michael Emerson, Sukhpal Prehar, Florence M. Baudoin, Min Zi, Nasser Alatwi, Luigi Venetucci, Kai Schuh, Judith C. Williams, Angel L. Armesilla, and Ludwig Neyses
Circulation. 2007;115:483-492; published online before print January 22 2007, doi:10.1161/CIRCULATIONAHA.106.643791
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Clinical Perspective
Activation of Nuclear Receptor Nur77 by 6-Mercaptopurine Protects Against Neointima Formation
Nuno M.M. Pires, Thijs W.H. Pols, Margreet R. de Vries, Claudia M. van Tiel, Peter I. Bonta, Mariska Vos, E. Karin Arkenbout, Hans Pannekoek, J. Wouter Jukema, Paul H.A. Quax, and Carlie J.M. de Vries
Circulation. 2007;115:493-500; published online before print January 22 2007, doi:10.1161/CIRCULATIONAHA.106.626838
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Clinical Perspective
Vascular Medicine:
FTY720, a Synthetic Sphingosine 1 Phosphate Analogue, Inhibits Development of Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice
Jerzy-Roch Nofer, Martine Bot, Martin Brodde, Paul J. Taylor, Paul Salm, Volker Brinkmann, Theo van Berkel, Gerd Assmann, and Erik A.L. Biessen
Circulation. 2007;115:501-508; published online before print January 22 2007, doi:10.1161/CIRCULATIONAHA.106.641407
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Clinical Perspective
Diverse Contribution of Bone Marrow–Derived Cells to Vascular Remodeling Associated With Pulmonary Arterial Hypertension and Arterial Neointimal Formation
Makoto Sahara, Masataka Sata, Toshihiro Morita, Kazuto Nakamura, Yasunobu Hirata, and Ryozo Nagai
Circulation. 2007;115:509-517; published online before print January 22 2007, doi:10.1161/CIRCULATIONAHA.106.655837
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Clinical Perspective
Basic Science for Clinicians:
Peroxisome Proliferator–Activated Receptors as Transcriptional Nodal Points and Therapeutic Targets
Jonathan D. Brown and Jorge Plutzky
Circulation. 2007;115:518-533, doi:10.1161/CIRCULATIONAHA.104.475673
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Congenital Heart Disease for the Adult Cardiologist:
Arrhythmias in Adult Patients With Congenital Heart Disease
Edward P. Walsh and Frank Cecchin
Circulation. 2007;115:534-545, doi:10.1161/CIRCULATIONAHA.105.592410
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Images in Cardiovascular Medicine:
Cardiac Leiomyosarcoma
Seth Goldbarg, Naveenta Kumar, and Samin Sharma
Circulation. 2007;115:e47-e48, doi:10.1161/CIRCULATIONAHA.106.637264
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Kussmauls Sign in Right Ventricular Dysfunction
Alex John-Patrick Rosenberg and Duwarakan K. Satchithananda
Circulation. 2007;115:e49-e50, doi:10.1161/CIRCULATIONAHA.106.654897
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Hemodynamic Consequences of Massive Coronary Air Embolism
Anand Prasad, Subhash Banerjee, and Emmanouil S. Brilakis
Circulation. 2007;115:e51-e53, doi:10.1161/CIRCULATIONAHA.106.655977
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Correspondence:
Letter by Guazzi and Reina Regarding Article, "Aspirin Use and Outcomes in a Community-Based Cohort of 7352 Patients Discharged After First Hospitalization for Heart Failure"
Marco Guazzi and Giuseppe Reina
Circulation. 2007;115:e54, doi:10.1161/CIRCULATIONAHA.106.646182
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Response to Letter Regarding Article, "Aspirin Use and Outcomes in a Community-Based Cohort of 7352 Patients Discharged After First Hospitalization for Heart Failure"
Finlay A. McAlister, William A. Ghali, Yanyan Gong, Jiming Fang, Jack V. Tu, and Paul W. Armstrong
Circulation. 2007;115:e55, doi:10.1161/CIRCULATIONAHA.106.657015
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European Perspectives:
European Perspectives
Circulation. 2007;115:f13-f16
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